Abstract
Mesonephric carcinomas, which derive from the remnants of the paired mesonephric (Wolfian) ducts, are a rare subtype of epithelial
tumors of the uterine cervix. Because of the few cases reported in literature; the therapy, prognosis and outcome are still not clear. 52
years old women underwent a type III radical hysterectomy, bilateral salpingo-oophorectomy and bilateral pelvic lymph node dissection
because of the cervical cancer was presented in our report. Mesonephric adenocarcinoma with no lymph node metastasis, no parametrial
tumoral spread and free surgical margins were reported in certain pathology. She did not receive adjuvant therapy. She has been
followed-up for 2 years without recurrence
References
- 1. Holland-Frei. Histological classifi cation of epithelial tumors. In: Kufe DW, Pollock RE, Weichsellbaum RR, et al. eds. Cancer Medicine. 6th edn. Hamilton (ON): BC Decker, 2003.
- 2. Yap OW, Hendrickson MR, Teng NN, Kapp DS. Mesonephric adenocarcinoma of the cervix: a case report and review of the literature. Gynecol Oncol, 2006; 103(3): 1155-8.
- 3. Dierickx A, Göker M, Braems G, Tummers P, Van den Broecke R. Mesonephric adenocarcinoma of the cervix: Case report and literature review. Gynecol Oncol Rep, 2016; 17: 7-11.
- 4. Fukunaga M, Takahashi H, Yasuda M. Mesonephric adenocarcinoma of the uterine cervix: a case report with immunohistochemical and ultrastructural studies. Pathol Res Pract, 2008; 204(9): 671-6.
- 5. Kenny SL, McBride HA, Jamison J, McCluggage WG. Mesonephric adenocarcinomas of the uterine cervix and corpus: HPV-negative neoplasms that are commonly PAX8, CA125, and HMGA2 positive and that may be immunoreactive with TTF1 and hepatocyte nuclear factor 1-beta. Am J Surg Pathol, 2012; 36(6): 799-807.
- 6. Park KJ, Kiyokawa T, Soslow RA, Lamb CA, Oliva E, Zivanovic O, Juretzka MM, Pirog EC. Unusual endocervical adenocarcinomas: an immunohistochemical analysis with molecular detection of human papillomavirus. Am J Surg Pathol, 2011; 35(5): 633-46.
- 7. Sedlis A, Bundy BN, Rotman MZ, Lentz SS, Muderspach LI, Zaino RJ. A randomized trial of pelvic radiation therapy versus no further therapy in selected patients with stage 1B carcinoma of the cervix aft er radical hysterectomy and pelvic lymphadenectomy: A Gynecologic Oncology Group Study. Gynecol Oncol 1999; 73:177-83.
Abstract
Mezonefrik karsinom mezonefrik (Wolf) kanalların kalıntılarından köken almakta olup servikal epitelial tümörlerin nadir bir alt tipidir.
Literatürde az sayıda hasta olduğundan; tedavi, prognoz ve sonuçlar hala net değildir. Bu makalede; 52 yaşında, servikal kanser nedeniyle
tip III radikal histerektomi, bilateral salpingoooferektomi ve bilateral pelvik lenf nodu disseksiyonu uygulanmış hasta sunuldu. Patoloji
sonucu servikal mesonefrik adenokarsinom olarak rapor edilen hastada lenf nodu tutulumu, parametrial tutulum ve cerrahi sınırlarda
tumor yoktur. Adjuvan tedavi uygulanmamıştır. Hasta 2 yıldır hastalıksız ve rekürrenssiz takip edimektedir.
Keywords
References
- 1. Holland-Frei. Histological classifi cation of epithelial tumors. In: Kufe DW, Pollock RE, Weichsellbaum RR, et al. eds. Cancer Medicine. 6th edn. Hamilton (ON): BC Decker, 2003.
- 2. Yap OW, Hendrickson MR, Teng NN, Kapp DS. Mesonephric adenocarcinoma of the cervix: a case report and review of the literature. Gynecol Oncol, 2006; 103(3): 1155-8.
- 3. Dierickx A, Göker M, Braems G, Tummers P, Van den Broecke R. Mesonephric adenocarcinoma of the cervix: Case report and literature review. Gynecol Oncol Rep, 2016; 17: 7-11.
- 4. Fukunaga M, Takahashi H, Yasuda M. Mesonephric adenocarcinoma of the uterine cervix: a case report with immunohistochemical and ultrastructural studies. Pathol Res Pract, 2008; 204(9): 671-6.
- 5. Kenny SL, McBride HA, Jamison J, McCluggage WG. Mesonephric adenocarcinomas of the uterine cervix and corpus: HPV-negative neoplasms that are commonly PAX8, CA125, and HMGA2 positive and that may be immunoreactive with TTF1 and hepatocyte nuclear factor 1-beta. Am J Surg Pathol, 2012; 36(6): 799-807.
- 6. Park KJ, Kiyokawa T, Soslow RA, Lamb CA, Oliva E, Zivanovic O, Juretzka MM, Pirog EC. Unusual endocervical adenocarcinomas: an immunohistochemical analysis with molecular detection of human papillomavirus. Am J Surg Pathol, 2011; 35(5): 633-46.
- 7. Sedlis A, Bundy BN, Rotman MZ, Lentz SS, Muderspach LI, Zaino RJ. A randomized trial of pelvic radiation therapy versus no further therapy in selected patients with stage 1B carcinoma of the cervix aft er radical hysterectomy and pelvic lymphadenectomy: A Gynecologic Oncology Group Study. Gynecol Oncol 1999; 73:177-83.
Details
| Primary Language | English |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | May 21, 2018 |
| Submission Date | March 14, 2017 |
| Published in Issue | Year 2016 Volume: 19 Issue: 3 |